How Pfizer and BioNTech made history with their vaccine

How Pfizer and BioNTech made history with their vaccine Watch the newest video from Big Think: https://bigth.ink/NewVideo Learn skills from the world's top minds at Big Think Edge: https://bigth.ink/Edge ---------------------------------------------------------------------------------- Wondering how Pfizer and partner BioNTech developed a COVID-19 vaccine in record time without compromising safety? Dr Bill Gruber, SVP of Pfizer Vaccine Clinical Research and Development, explains the process from start to finish. “I told my team, at first we were inspired by hope and now we’re inspired by reality,” Dr Gruber said. “If you bring critical science together, talented team members together, government, academia, industry, public health officials—you can achieve what was previously the unachievable.” The Pfizer-BioNTech COVID-19 Vaccine has not been approved or licensed by the Food and Drug Administration (FDA), but has been authorized for emergency use by FDA under an Emergency Use Authorization (EUA) to prevent COVID-19 for use in individuals 12 years of age and older. The emergency use of this product is only authorized for the duration of the emergency declaration unless ended sooner. See Fact Sheet: cvdvaccine-us.com/recipients. ---------------------------------------------------------------------------------- BILL GRUBER: Dr. Bill Gruber is senior vice president of Pfizer Vaccine Clinical Research and Development, and is responsible for global clinical development of vaccines. Dr. Gruber was previously an associate professor of pediatrics at Vanderbilt University School of Medicine and also served as the director of the Diagnostic Virology Laboratory at Vanderbilt University Hospital. Dr. Gruber received his bachelor degree in mathematical sciences from Rice University, Houston, Texas, and his medical degree from Baylor College of Medicine, Houston, Texas. He is board-certified in pediatrics and pediatric infectious diseases and has authored or co-authored 140 original research articles and numerous invited articles and book chapters. ---------------------------------------------------------------------------------- TRANSCRIPT: ---------------------------------------------------------------------------------- ABOUT BIG THINK: Smarter Faster™ Big Think is the leading source of expert-driven, actionable, educational content -- with thousands of videos, featuring experts ranging from Bill Clinton to Bill Nye, we help you get smarter, faster. ​Subscribe to learn from top minds like these daily. Get actionable lessons from the world’s greatest thinkers & doers. Our experts are either disrupting or leading their respective fields. ​We aim to help you explore the big ideas and core skills that define knowledge in the 21st century, so you can apply them to the questions and challenges in your own life. Other frequent contributors include Michio Kaku & Neil deGrasse Tyson. Michio Kaku Playlist: https://bigth.ink/kaku Bill Nye Playlist: https://bigth.ink/BillNye Neil deGrasse Tyson Playlist: https://bigth.ink/deGrasseTyson Read more at Bigthink.com for a multitude of articles just as informative and satisfying as our videos. New articles posted daily on a range of intellectual topics. Join Big Think Edge, to gain access to an immense library of content. It features insight from many of the most celebrated and intelligent individuals in the world today. Topics on the platform are focused on: emotional intelligence, digital fluency, health and wellness, critical thinking, creativity, communication, career development, lifelong learning, management, problem solving & self-motivation. BIG THINK EDGE: https://bigth.ink/Edge ---------------------------------------------------------------------------------- Follow Big Think here: 📰BigThink.com: https://bigth.ink 🧔Facebook: https://bigth.ink/facebook 🐦Twitter: https://bigth.ink/twitter 📸Instagram: https://bigth.ink/Instragram 📹YouTube: https://bigth.ink/youtube ✉ E-mail: info@bigthink.com

Protecting space stations from deadly space debris

Protecting space stations from deadly space debris Watch the newest video from Big Think: https://bigth.ink/NewVideo Learn skills from the world's top minds at Big Think Edge: https://bigth.ink/Edge ---------------------------------------------------------------------------------- This is the first episode of Just Might Work, an original series by Freethink, focused on surprising solutions to our biggest problems. Catch more Just Might Work episodes on their channel: https://www.youtube.com/channel/UConJDkGk921yT9hISzFqpzw ---------------------------------------------------------------------------------- TRANSCRIPT: ASTRONAUT: Mission abort. Repeat. Mission abort. HOST: In the opening scene of Gravity, a collision with space debris leads to chaos. ANNOUNCER: Debris from the missile strike has caused a chain reaction, hitting other satellites and creating new debris. HOST: Unfortunately this scenario isn't just made up movie drama. What if I told you this was one of the most dangerous things in space? It's a paint chip. It doesn't look like much, but debris like this can be catastrophic when orbiting Earth nearly 10 times the speed of a bullet. Space has become humanity's biggest junkyard, and the debris problem is just getting worse. So some scientists are turning from exploration to mitigation. MURIEL RICHARD-NOCA: The ClearSpace-1 servicer is a space robot. That's a huge step toward the space sustainability. HOST: This space robot leads the way in an ambitious and complicated mission to clean up space before it's too late. This is Just Might Work, a show about surprising solutions to our biggest problems. JOHN CRASSIDIS: In the early days, nobody ever thought this would happen. Everybody said space is big. Well it's getting a lot smaller. In the sense that it's getting more and more crowded. HOST: There are an estimated 128 million pieces of space junk in orbit. That includes things like decommissioned satellites, the ashes of Star Trek's creator, and one of Elon Musk's Tesla Roadsters. Astronauts also have lost a bunch of stuff, like a tool bag. ASTRONAUT 1: Um, we have a lost tool. HOST: And a camera. ASTRONAUT 2: Uh, Suni your camera is behind you. I hope it's tethered. ASTRONAUT 3: It's not. Oh great. HOST: But the big danger is the 99 percent of debris that is smaller than 10 centimeters and can't be tracked. They're flying around space at nearly 18,000 miles per hour. And we don't know where they are until they hit something. CRASSIDIS: The issue is, you can have one orbit where the satellite is going around the equator, and another one that's going around the poles, and that's a terrible situation, that's a t-bone intersection. So a very small piece of debris can potentially wipe out a very big satellite. HOST: Of the more than 500 collisions and breakups and explosions in space, one of the most consequential was in 2009 when the Iridium 33 communication satellite collided with a defunct Russian satellite, creating thousands of new pieces of space debris. The International Space Station actually had to move a few times to avoid that debris field because it endangered the lives of astronauts on board. Since we can't track the small stuff, we can't clean it up yet. So the plan is to start with the bigger pieces to avoid the collisions that create more untraceable debris. LUC PIGUET: The question was, where should we start? Right? Most of the small pieces of debris are actually resulting from fragmentation events of large pieces of debris. This means that, if you remove one large piece of debris, you remove thousands of potential future pieces of debris. RICHARD-NOCA: What we're bringing in, with the ClearSpace-1 mission is the concept of the tow truck. If you have a mechanical failure, it is okay to leave the car on the freeway. There is always, for you, the opportunity to call the tow truck service to help you remove your car from the freeway. So, ClearSpace-1 is really bringing that tilting point where operators will have now the opportunity to do more than just repairing it, but actually removing it. HOST: The ClearSpace mission in partnership with the European Space Agency is to capture, then remove a secondary payload adapter left in orbit by the Vega Rocket in 2013. And that's a more complicated undertaking than it sounds. RICHARD-NOCA: The trickiest part, which will be the capture, that will be done autonomously. The object you're trying to capture is tumbling, so you're in the case where you're stable, but the object is tumbling so you need to recognize what the tumbling is such that you decide to do a maneuver to match your motion with the velocity of your object. And at that point, you can open the forearms and then go and trigger the capture, and then you slow down the... To read the full transcript, please visit https://ift.tt/3gHAoFG

Qasim Ali Shah Talk with Syed Sarfraz Shah about Forgiveness, Marriage & Handling Grief

Syed Sarfraz Shah and Qasim Ali Shah are talking on different issues related to Forgiveness, How to select spouse and how to handle grif. https://ift.tt/2R3s86g To Get Updated with New Lectures, Sessions and Videos Fill the Form. Qasim Ali Shah is not just a Motivational Speaker but an enthusiastic doer. He followed his passions and proved his self a Successful Entrepreneur, Inspiring Teacher, Best-Selling Author, Philanthropist and a Transformational Trainer. Follow Us On Social Media : https://ift.tt/1HAPumV https://ift.tt/3boEkpZ https://twitter.com/QasimAliShah_ https://twitter.com/qasfoundation https://ift.tt/2Wqt4p2 https://ift.tt/2Wqeei1 https://ift.tt/35QV7Ro https://ift.tt/2YTR716 https://ift.tt/2WpbS37 https://ift.tt/2Z7PwVJ

Starting a Business - How to Prepare Yourself for Starting Business - Qasim Ali Shah

https://ift.tt/2R3s86g To Get Updated with New Lectures, Sessions and Videos Fill the Form. Qasim Ali Shah discussing with Weekly Class participants about How we can prepare ourselves for Business during Job/Naukari. Qasim Ali Shah is not just a Motivational Speaker but an enthusiastic doer. He followed his passions and proved his self a Successful Entrepreneur, Inspiring Teacher, Best-Selling Author, Philanthropist and a Transformational Trainer. Follow Us On Social Media : https://ift.tt/1HAPumV https://ift.tt/3boEkpZ https://twitter.com/QasimAliShah_ https://twitter.com/qasfoundation https://ift.tt/2Wqt4p2 https://ift.tt/2Wqeei1 https://ift.tt/35QV7Ro https://ift.tt/2YTR716 https://ift.tt/2WpbS37 https://ift.tt/2Z7PwVJ

Importance of Good Reputation & Character for Success in Business - Qasim Ali Shah

Enablers contact info: Learn the Art of eCommerce in Local and International Markets Start from here: https://ift.tt/2NlAS68 Enablers Support Team ------------------------- Support@enablers.org Qasim Ali Shah session with Ecommerce students about success in Business. He share 2 important factors for success Good Character & Good Reputation. So if you want to succeed in business you must have to work on these. https://ift.tt/2R3s86g To Get Updated with New Lectures, Sessions and Videos Fill the Form. Qasim Ali Shah is not just a Motivational Speaker but an enthusiastic doer. He followed his passions and proved his self a Successful Entrepreneur, Inspiring Teacher, Best-Selling Author, Philanthropist and a Transformational Trainer. Follow Us On Social Media : https://ift.tt/1HAPumV https://ift.tt/3boEkpZ https://twitter.com/QasimAliShah_ https://twitter.com/qasfoundation https://ift.tt/2Wqt4p2 https://ift.tt/2Wqeei1 https://ift.tt/35QV7Ro https://ift.tt/2YTR716 https://ift.tt/2WpbS37 https://ift.tt/2Z7PwVJ

The science of sex, love, attraction, and obsession | Big Think

The science of sex, love, attraction, and obsession | Big Think Watch the newest video from Big Think: https://bigth.ink/NewVideo Learn skills from the world's top minds at Big Think Edge: https://bigth.ink/Edge ---------------------------------------------------------------------------------- How love makes us feel can only be defined on an individual basis, but what it does to the body, specifically the brain, is now less abstract thanks to science. One of the problems with early-stage attraction, according to anthropologist Helen Fisher, is that it activates parts of the brain that are linked to drive, craving, obsession, and motivation, while other regions that deal with decision-making shut down. Dr. Fisher, professor Ted Fischer, and psychiatrist Gail Saltz explain the different types of love, explore the neuroscience of love and attraction, and share tips for sustaining relationships that are healthy and mutually beneficial. ---------------------------------------------------------------------------------- TIMESTAMPS: 0:00 Intro 0:32 Ted Fischer on love versus lust 0:56 Gail Saltz talks love and neurotransmitters 4:39 Helen Fisher on how love shuts down decision-making parts of our brains 8:15 Saltz on the science of a “good partner” 10:18 Helen Fisher on the importance of sex and romance for the brain and your relationship ---------------------------------------------------------------------------------- TRANSCRIPT: During romantic or passionate love, you're gonna feel the sense of being addicted to your partner. People who are madly in love can fall madly in love with somebody who's married, who lives on the other side of the planet, who comes from a different religion. And somehow, they'll say to themselves, we'll work it out, we can work this out. Because of all that energy of intense romantic love. Over time, as this whole neurotransmitter thing settles out, what's left? TED FISCHER: We define romantic love as an intense desire for another, with the expectation that it's gonna persist into the future. And that distinguishes it from lust, which is generally fleeting, and also for more companionship love, which doesn't have that intensity of desire, that you want to possess the other in some way. GAIL SALTZ: Studies have looked at activity in the brain when recalling passionate or romantic love, versus say maternal love, and finds that different centers definitely are more active. And they would, say, put people into the functional MRI, and they said, think about your partner, or think about your lover. And certain areas lit up, or they said, think about your mom, and different areas lit up. Which is important, because different areas are responsible for the release of different neurotransmitters. Which then come to affect your future feeling states and future behaviors. During romantic or passionate love, what happens from a neurotransmitter standpoint, those chemicals that are released when you have that particular experience? Dopamine goes up. Dopamine is essentially the neurotransmitter of reward. So it is a neurotransmitter that's released when you have new or novel experience, but particularly experiences that are reinforcing. Like gambling. Or something that is really addictive. In fact, literally addictive. It's the neurotransmitter if you snorted cocaine that is most responsible for, wow, that was great, and I totally wanna do it again. So that is a neurotransmitter that definitely goes up when you are in the throes of romantic or passionate love. And what does that mean for you? It means that you're gonna feel the sense of being addicted to your partner. And in fact, it's also the neurotransmitter that goes up for people who have obsessive compulsive disorder. Does that mean you're gonna develop OCD? No. But what it does mean is you're probably going to obsess over your partner. In comes another neurotransmitter, that's called serotonin. It is definitely a neurotransmitter that is active for obsessive compulsive disorder. And for depression. Do you become depressed? No, you really don't. But what you do do is a feature of depression called rumination. So you think about your partner over and over and over again in this really obsessive manner. And, if your partner is separated from you, you're going to have this longing, where you're wanting to be with them, kind of like you'd want to be with a drug if it was taken away from you and you were already addicted to it. There are changes in other neurotransmitters as well. So if you're physically with your partner, the neurotransmitter oxytocin, which is kind of known as the cuddle neurotransmitter, and that makes you feel warm, and snuggly, and intensely bonded to this person. It is particularly released following orgasm. So, you know, if you're having sex with your partner, and things go well, you're gonna feel very... To read the full transcript, please visit https://ift.tt/3wlmFed

Baba Irfan ul Haq discussing on Food & Mental Health with Qasim Ali Shah - Part 2 of 2

Watch Part 1 here: https://youtu.be/mf6Vi2TBd-4 Qasim Ali Shah and Baba Irfan ul Haq discussing on importance of simple food and issues related to mental health. Qasim Ali Shah is not just a Motivational Speaker but an enthusiastic doer. He followed his passions and proved his self a Successful Entrepreneur, Inspiring Teacher, Best-Selling Author, Philanthropist and a Transformational Trainer. Follow Us On Social Media : https://ift.tt/1HAPumV https://ift.tt/3boEkpZ https://twitter.com/QasimAliShah_ https://twitter.com/qasfoundation https://ift.tt/2Wqt4p2 https://ift.tt/2Wqeei1 https://ift.tt/35QV7Ro https://ift.tt/2YTR716 https://ift.tt/2WpbS37 https://ift.tt/2Z7PwVJ